![]() ![]() Even though the antidepressant is working right away, it takes some time to manifest in your mood and behaviors. ![]() Over time, your brain makes new connections associated with these positive interpretations.Īs new nerve pathways are formed, your mood and behaviors improve.īut, it may take a few weeks for you to experience these changes. Scientists believe that having more neurotransmitters freely available in your brain helps you make more positive interpretations of your experiences. ![]() SNRIs do the same with serotonin but also norepinephrine. SSRIs work by preventing serotonin from being taken up by nerve cells, so more serotonin is available to send messages. This makes a difference in terms of how long antidepressants take to work. Newer antidepressants work on other types of neurotransmitters, such as: Neurotransmitters help transfer messages from nerve cells to other cells in your brain and body.Įxamples of neurotransmitters commonly affected by antidepressants include: You may feel their effect on your mood within hours or days of receiving your first dose.ĭifferent types of antidepressants work on different chemicals in your brain called neurotransmitters. However, a newer class of antidepressants known as N-methyl-d-aspartate (NMDA) receptor blockers may work faster in some cases. Many of them, such as selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), generally take about 2 to 8 weeks to work. Or at least, you may not notice the changes right away. Most antidepressants don’t work right away. ![]()
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